Fluorescence imaging in combination with polarization microscopy revealed that zebra stripes consist of alternating domains of highly bent filaments that correspond to low filament density and low nematic order next to domains of straight filaments at comparatively large filament density and nematic order [ 143].
This is because there is no distinction between co-occurring domains that are positioned next to the domain of interest and co-occurring domains found at distant sites within a protein.
A previously discussed putative homologue in Stramenopiles has a START domain next to its RasGAP domain, not the unrelated CRAL/TRIO domain found in NF1 (van Dam et al., 2011 ).
It is noteworthy that XopD165-175 sequence, as its homologous sequence in MarR proteins, is located next to a domain (KAE-rich) involved in protein dimerization that may adopt a α-helical structure, based on its homology with the TolA protein family.
It should be noted that, next to the domain of attention, we found no further interaction effect of Time × Group.
Twelve members of the mammalian SNX family (SNX1, 2, 4 9, 18, 30, 32 and 33) contain a BAR (Bin, amphiphysin, Rvs) domain next to the PX domain and they are grouped into the PX-BAR subfamily of SNXs.
The fractions of reads with GH13 domain along with CBM48 (WS-72: 39%, GL-72: 46%) were the most abundant next to GH13 domains (WS-72: 17%, GL-72: 17%) that were predicted independently.
Interestingly, when Oyen and colleagues [51] analyzed the sporulation-specific functions of Sso1, they found that next to functional domains within the protein itself, the 3'UTR of the sso1 mRNA is essential for sporulation and this function cannot be rescued by the 3'UTR of its close paralogue, sso2, which does not have a meiosis-specific function.
Although autocatalytic cleavage is not absolutely required and conserved, the presence of the GPS immediately next to TM domains is highly specific for aGPCR and PKD1.
In particular both kinases harbor a calmodulin-binding sequence and an autoregulatory domain (ARD) next to the catalytic domain and are therefore regulated by calmodulin (or proteins with calmodulin-like domains).
