Sentence examples for next nucleotide from inspiring English sources

The probability that the next nucleotide is a, where a ∈ Ω = {A, C, G, U}, conditioned on the context v ∈ Ω m is {p}_{mathbf{v},a}=frac{N_xleft(mathbf{v}aright)+updelta }{N_xleft(mathbf{v}right)+4delta }. (7).

These nicks consist of the 3'-hydroxyl group of the last nucleotide added to the chain and the 5'-phosphate group of the next nucleotide on the adjacent chain.

Superpositioning of structures of yeast eIF3b-RRM with hnRNP A1 (UP1) complexed with single-stranded telomeric DNA (PDB code 2UP1) suggests it to bind in the same manner to an oligonucleotide, with Phe 126 stacking against the sugar pocket of one nucleotide and Phe 128 against the base of the next nucleotide, whilst the Lys 124 would neutralize the backbone phosphate (Figure 7B).

Templates, primer-ends and nucleotides are positioned at the active site, the 3' hydroxyl of the primer-end attacks the α-phosphate of the incoming dNTP, pyrophosphate (PPi) is released and the primer-end translocates to allow for the addition of the next nucleotide [1].

2. Add S concatenated with the next nucleotide in the genome as a new, previously unobserved, phrase into the dictionary.

Upon the release of the PPi, TEC is reset to the pre-translocated state (TECn+1,0) and ready for the next nucleotide addition cycle.

The analysis of the next nucleotides also indicated a specificity for the palindromic trinucleotides TGC/GCA (see Table S2).

That is, the context information looks for Gs within the two next nucleotides to the right of each C (or it looks for Cs within the two next nucleotides to the left of a G) in the input files.

Studies with the exocyclic acrolein-derived deoxyguanosine adduct γ-hydroxy-1, N-propano-2′-deoxyguanosine (γ-HOPdG) and its structural analogues suggest that the kinetics of nucleotide insertion and next base extension by both yeast and human pol η may be influenced by ring opening of the exocyclic adduct (26, 27, 49).

Introduction of TAMs increases RT-catalyzed ATP-dependent removal of chain-terminating NRTIs as well as reducing the inhibition of NRTI removal by the next complementary nucleotide [13].

Mutations of residues 67 and 70, both in the fingers subdomain and near residue K65 (Fig. 1A), were found to have the greatest effect on increasing unblocking [13], while a T215F substitution in the palm subdomain is largely responsible for the reduced inhibition by the next complementary nucleotide [14].