Next, we generated two derivative cell lines following infection of T47D with lentiviral vectors encoding p21Cip1 shRNA T47D-p21shh) or a scrambled control (T47D-scr).
Next, we generated tumor organoids using single cells derived from adenomas of ApcMin mice.
Next, we generated liver-specific MnSOD-deficient mice by crossbreeding with Alb Cre transgenic mice.
Next, we generated a stable HCT116 line conditionally expressing p53 in the presence of tetracyclin (HCT116-p53ind).
Next, we generated two single-residue BFL1ΔC mutants: R88D, localized in the BH1 motif of the canonical BH3-binding groove (Fig. 1e, red); and L21A, localized at the BH4 motif purportedly implicated in BAX retrotranslocation by BCL2 (Fig. 2e, cyan).
Next, we generated a panel of humanized scFvs and tested in vitro for their ability to direct CAR-T cells to specifically lyse, proliferate, and secrete cytokines in response to antigen-bearing targets.
Next, we generated reports for the most frequently utilized codes and summarized each code's findings.
Next, we generated a receiver-operator curve (ROC) to visually represent the trade-off between sensitivity and specificity.
Next, we generated a final consensus model for each species.
Next, we generated microarray expression profiles of adult testis from F0 and F1 males.
Next, we generated a series of 5' promoter deletion constructs to assess the importance of the putative Foxj1-binding sites.
