Stratified results by prepregnancy BMI suggested that when underweight women increase GWG, they might release more POPs from their fat deposits into bloodstream and transfer them to their newborns, relative to other BMI categories.
Since vascular contraction induced by α1-adrenergic receptor activation may be offset by a simultaneous NO release from the endothelium (10, 34, 40), we explored the possibility that a decrease in this NO-dependent vasodilatation opposing α1-adrenergic-induced constriction may explain, in part, the enhanced femoral vascular response in the newborn llama relative to the newborn sheep.
This was confirmed by TaqMan qRT PCR: amplification failed in MatDp(dist2) newborn brain due to a lack of Blcap_v2a transcripts, while an approximately 2-fold increase of Blcap_v2a was observed in PatDp(dist2) newborn brain relative to the non-UpDp control (Fig. 3A).
Although child and newborn health ranked the lowest relative to the other categories, the difference between each ranking was less than one.
The prevalence of newborns whose BW was < 85% relative to the mean weight was higher for the African Americans (n = 28, 13%) compared with the Dominicans (n = 39, 10%).
Among the transcripts down-regulated in the MRL/MpJ mouse relative to the adults, newborns, and embryos of the reference strain (Additional file 2), we found a remarkable overrepresentation of KRAB genes but none of those was associated with immune and wounding response.
In order to track for the neonatal and embryonic paralleles in the adults of the MRL/MpJ mouse, we focused on the transcripts which were differentially regulated in newborns, embryos and the MRL/MpJ adults relative to the adults of the control strains.
We also performed microarray analysis on RNA isolated from the rib chondrocytes of newborn and 5-day-old mice that were either heterozygous (5 day) or homozygous new born (newborn and 5 day) for Comp D469Del relative to the wild-type controls.
This merging of data could result in an underestimation of the number of cases detected relative to the experience of both newborn hearing screening programmes.
Before the measurements were performed, the newborn was placed on a small wedge-shaped cushion at an angle of 30° relative to the horizontal plane.
