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Would routine newborn sequencing be cost-effective?
Her newborn sequencing study, part of the NIH-funded quartet, enlists many parents during prenatal clinical visits.
"These are still very early days if more people do this and the discrimination and confidentiality risks do not materialize, then presumably more people will choose newborn sequencing".
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As a part of its new financing, Bina announced a new partner in Liz Worthey at the Medical Center of Wisconsin, who focuses on newborn whole genome sequencing in the neonatal intensive care unit (NICU).
BabySeq is one of four projects funded by the National Institutes of Health (NIH) 3 years ago to probe the risks and benefits of sequencing newborns' DNA and compare the results to conventional newborn disease screening using biochemical analysis of blood spots.
Parents welcoming a new baby into their family are no longer content to count fingers and toes to assess their infant's state of health: In a survey released Thursday, nearly half said they would be "very" or "extremely" interested in having their newborn's genome sequenced, and fully a third more pronounced themselves "somewhat" interested.
And as genomics starts to create real opportunities to deliver better patient care – the US National Institutes of Health last week announced pilot studies to evaluate sequencing of newborn babies – there is a danger that these fears will divert us from more pressing issues that we need to think through.
In an interview, he said the National Institutes of Health has awarded several research grants for DNA sequencing of newborn blood, which could facilitate the earliest possible diagnosis of health-threatening problems.
A new $25 million National Institutes of Health research program will explore the promise and ethical challenges of sequencing every newborn's genome.
A new research program funded at $25 million over 5 years by the National Institutes of Health (NIH) will explore the promise and ethical challenges of sequencing every newborn's genome.
When it comes to precisely counting about 50 new mutations out of 3.2 billion bases in a newborn's genome, current sequencing methods are at the limit of their ability to filter out true mutations from mistaken ones and may be discounting a statistically significant number of actual mutations, Krause says.
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