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Since then 135 people, mostly from Britain, have died from the new prion disease.
It expects to follow that route with its new prion procedure.
But since 1994 two dozen people 23 in Britain and 1 in France have died from a new prion disease, known as new-variant CJD (nvCJD), and others appear to be sick with it.
SALVATORE MONACO, a researcher at the University of Verona, and his colleagues, have created a stir this week by reporting, in the latest edition of the Proceedings of the National Academy of Sciences, what they think is a new prion disease in cattle.The best known (indeed, until now the only known) prion disease of cattle is bovine spongiform encephalopathy (BSE), or "mad cow" disease.
This suggests that duplication of aggregation-prone segments might represent a simple mechanism for evolving new prion domains, potentially explaining why oligopeptide repeats are frequently found in prion proteins.
Meanwhile, a new prion disease named Psychotic Outburst Syndrome (or POS) is affecting dogs, causing friendly pets to become violent.
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The authors experimentally investigated 100 prion protein candidates and found 19 new prions.
Following the BSE epidemic in the UK a new human prion disease, variant CJD (vCJD), was recognised as an acquired prion disease cause by exposure to BSE-contaminated material.
We were intrigued by the possibility of Mca1 from S. cerevisiae being a potential new yeast prion protein and set out to examine the aggregation and prion properties of this protein more closely.
This evidence in favor of a new bovine prion strain in cattle suggests that BSE is not the only transmissible prion disease in cattle.
Not only that, but in the current issue of Molecular Cell, the Lindquist lab has identified a new yeast prion and shown that a segment of this protein also confers prionlike activity.
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