Sentence examples for new leads of from inspiring English sources

Additionally, the change of para-substituent group of acylhydrazone framework permitted us to identify hydrophilic carboxylate derivative (6g) and hydrophobic bromo derivative (6b) as two new leads of analgesics more active than dipyrone used as standard and with selective peripheral or central mechanism of action.

Discovery and development of a new leads of antimicrobial drugs as well as many others could be better explained by reverse pharmacology which is an evolutionary process, based on traditional knowledge which facilitates not only to search experimental database for many novel leads but also minimize time, money and toxicity since several years.

Since the activation and proliferation of RASFs has been implicated in the pathogenesis of rheumatoid arthritis, further in-depth follow-up analysis of the transcriptional regulation reported in this study may shed light on molecular pathogenic mechanisms underlying synovial fibroblasts in arthritis and provide new leads of potential therapeutic targets.

Our results provide new leads on the effect of Rac1 on osteoblastic differentiation in C2C12 cells.

A series of 2- 1,4′-bipiperidine-1′-yl thiazolopyridines 2- 1,4′-bipiperidine-1′-yl thiazolopyridines 2- 1,4′-bipiperidine-1′-yl thiazolopyridines 2- 1,4′-bipiperidine-1′-yl thiazolopyridines 2- 1,4′-bipiperidine-1′-yl thiazolopyridines

Ms Needham said they were now working on a new lead of a photo of a mystery boy who resembles Ben.

Quinolin-4-yl-substituted compounds constitute a new lead of cytotoxic and CDK inhibitor compounds from which more compelling and selective inhibitors can be designed.

Further SAR study demonstrated that lactone type of Michael acceptor provided a new lead of anti-EV71 drug candidates with high anti-EV71 activity in cell-based assay and enhanced mouse plasma stability.

This information may provide new leads for improving of the course.

All together we provide new leads for the discovery of novel antimalarials.

Additionally, DGE profiling provides new leads for functionally studies of genes involved in abiotic stress.