Sentence examples for new duplications from inspiring English sources

In contrast, in S. meliloti, the level of gene duplication diversity was similar to the level of nucleotide diversity (table 1), in spite of potentially strong purifying selection acting against new duplications.

Recently, the use of array technologies has led to the detection of new duplications in mentally retarded patients and the description of new syndromes, i.e. MECP2 duplication syndrome [ 23].

For example, Hooper and Berg (2003) looked at the age distribution of paralogs and concluded that most new duplications are rapidly deleted and estimated that only approximately 1/1,000 duplications are beneficial in E. coli.

This means that not only did we initially screen out sequences matching transposable elements but also we may not have captured enough sequence from these new duplications to detect TEs near to the identified break points.

In F470, we did not find any new duplications (Additional file 2: Table S4A), but did observe that the duplication on LGI was lost, resulting in a wild-type copy number for this region (Additional file 2: Table S4A).

The combined use of synteny and phylogenetic information makes it possible to delineate old and new duplications, identify translocations of genes and also allows investigation of gene families with only two members.

In rare cases, a new protein may act as outgroup to two existing trees and fuse them through a new duplication node.

In another family, an out of frame new duplication of 7 bp in exon 7 which generates a stop codon 17 bp upstream (c. 301_307dupCCCACTG) was found.

To examine this issue in more detail, we developed a new duplication-divergence model named the degree-dependent duplication (DDD) model by modifying the NHD model that we proposed previously [ 14].

Each advent of a whole genome duplication is subsequently followed by a gradual gene loss; this rediploidization ultimately promotes a new duplication, allowing the process to repeat in a cyclical manner [ 16].

Splitting of these clusters based on relative similarity can distinguish between older and newer duplication events and is implemented in the widely used Inparanoid algorithm [ 1] and related approaches [ 2].