Nevertheless, STAT3 is not required for Bcl6 expression in B cells and germinal center formation, as mice or humans with STAT3 deficiency have germinal centers [46], [75].
Nevertheless, immigrant emigration is not required for there to be a decrease in the fraction of less-educated immigrants.
Although the presence of chylomicrons is necessary for the development of hypertriglyceridaemic pancreatitis and these are considered to be present when the triglycerides >11.29 mmol/L, it is common in out-patient clinics to see patients with much higher concentrations who are nevertheless asymptomatic and have not required admission for hypertriglyceridaemic pancreatitis.
Nevertheless, activated caspase 8 was not required for most of the death when TNF was added to cells with elevated RIPK3, because Q-VD-OPh was not able to prevent their death, and cell death still occurred even in the caspase 8−/− MEFs.
Animal ethics permits for invertebrates are not required in Australia, nevertheless our field work protocol adheres to the ASAB ethics guidelines (http://asab.nottingham.ac.uk/ethics/guidelines.php), whereby we minimized the impact on individuals and populations by using the least disruptive technique.
Altogether, this work indicates that the GlyRS WHEP domain, although not required for secretion, nevertheless is integral to pre-synaptic accumulation of muscle-expressed mutant GlyRS.
Nevertheless, we found that RIPK1 was not required for JNK activation, and consequently that SP600125 also provided partial protection to apoptosis induced by TNF and BFA in the RIPK1-repressing cells.
Nevertheless, the observation that conjugation is not required in the context of influenza adjuvantation is fortuitous with regard to regulatory and production considerations; it would conceivably be much easier to achieve compositional standardisation across batches of GLP-produced vaccine if 'production' merely entailed mixing two homogenous GLP products together.
Nevertheless, we show that the CXXC domain is not required for enzymatic activity of Tet1 in vivo.
Nevertheless, it should be noted that SA signaling is not required for resistance to all hemi-biotrophic pathogens [24].
