Sentence examples for neutralizing potential from inspiring English sources

Prior to the development of in vitro infection systems, the neutralizing potential of HCV-specific antibodies were evaluated using "neutralization of binding" assays (NOB), where antibodies were screened for their ability to prevent recombinant viral E2 glycoprotein binding to mammalian cells (Rosa et al., 1996).

Neutralizing potential opposition makes construction permits easier to get, developers acknowledge.

Thus, even if direct experimental evidence of the neutralizing potential of anti-HVR1 antibodies by active immunization is still missing, the generation of a vaccine candidate with a cross-reactive potential would be highly desirable.

We focused in this work on the bulk neutralizing potential ratio (NPR), which is defined as the ratio of the content of non-acid-generating minerals (typically reactive carbonates such as calcite) to the content of potentially acid-generating minerals (typically sulfides such as pyrite).

To identify an ideal vaccine candidate, we have constructed five different versions of RBD fragments, S350-588-Fc, S358-588-Fc, S367-606-Fc, S377-588-Fc, anames77-588-Fc (theindicate indicatheireiresidueue range in the spike protein and their C-terminal Fc tag), and further investigated their receptor binding affinity, antigenicity, immunogenicity, and neutralizing potential.

Taken together, our data suggest that the RBD fragment encompassing spike residues 377-588 is a critical neutralizing receptor-binding fragment and an ideal candidate for development of effective MERS vaccines, and that adding non-neutralizing structures to this RBD fragment diminishes its neutralizing potential.

ABA includes techniques that measure the reactive sulfur content (which is converted to the acid-producing potential, Maximum Potential Acidity or MPA) and the reactive carbonate content (which is converted to acid-neutralizing potential, Neutralization Potential or NP).

Further, the quantification of neutralizing potentials clearly revealed below cloud processes in which crustal and anthropogenic components are responsible for the neutralization of anions.

ABA is an analytical procedure that provides an assessment of the acid-producing and acid-neutralizing potential of soils, sediments and rocks prior to coal mining, highway construction, and other large-scale earth-moving excavations.

These constituents have effect-enhancing and/or side effect-neutralizing potential [ 18- 20], and herbal remedies are considered relatively safe in prolonged use [ 19].

When neutralizing responses and immune protection are of interest, SEAP-NA is the most comprehensive measure of neutralization potential but is laborious and costly; cLIA is more efficient but measures only a subset of neutralizing antibodies (i.e., antibodies that bind to one neutralizing epitope).