Sentence examples for neutralization mechanisms from inspiring English sources

To gain a better understanding of this, we will analyze (1) the neutralizing epitopes in MPER and neutralization mechanisms of MPER-specific bNAbs and (2) limitations in the elicitation of neutralizing antibodies.

This review will focus on recent progress in the field from the following perspectives: (1) MPER structure and its role in membrane fusion, (2) the neutralizing epitopes in MPER and neutralization mechanisms of MPER-specific bNAbs, as well as the limitations in eliciting neutralizing antibodies, and (3) different strategies for MPER vaccine design and current harvests.

In this review, we summarize recently reported antibody antigen complex structures, their likely neutralization mechanisms and enhancement propensities, as well as their prophylactic and therapeutic capabilities in mouse models.

The neutralization mechanisms of bNAbs highlight the importance of membrane and show the role of lipids as a native scaffold to shape the structure of MPER, in turn suggesting the importance of lipids in immunogen design.

In our experiments, the amount of 1 N HCl used to neutralize metabolic alkalinity was roughly the same in the citrate and benzoate fermentations, probably due to the above neutralization mechanisms in citrate-grown cells.

In conclusion, recent substantial progresses involving the analyses of structure and immunology of MPER, particularly, the structure of this region bound by three MPER-specific bNAbs (2F5, 4E10 and 10E8), their epitopes, and their neutralization mechanisms.

Anti-MPER bNAbs share a common neutralization mechanism in which interactions of CDRH3 hydrophobic residues with membrane lipids seem to be essential32,55,56,57,58,59.

Importantly, 2D22 interferes with the viral expansion process and offers a basis for its neutralization mechanism.

The 310 helix rearranges in GPCL when bound to NPC1, and stabilization of this region by ADI-15946 CDR H3 may be part of the mAb's neutralization mechanism (Fig. 3a 12,16,20.

Identifying the neutralization epitope of EF13D on EF improves our understanding of the neutralization mechanism and has implications for vaccine development.

The results support a polymer bridging mechanism with high molecular weight polyelectrolytes and a charge neutralization mechanism with low molecular weight precipitant.