Sentence examples for neutral variants from inspiring English sources

The explosion of deep sequencing and genotyping increasingly requires the distinction between effect and neutral variants.

Fig. 1 When an advantageous mutation occurs, it rises to high frequency, dragging along nearby neutral variants.

Eventually, every individual in the population has the same mutation and the nearby neutral variants that "hitchhiked" with it.

For example, when an advantageous mutation occurs, natural selection can push that mutation to high frequency, dragging along nearby neutral variants (Smith and Haigh 1974).

Conversely, neutral variants located far away from the advantageous mutation do not hitchhike because recombination can break apart the association and therefore maintain variation.

CNV are not totally neutral variants.

Individuals serve as little more than vehicles for the cultural transmission of selectively neutral variants.

For neutral variants the estimated allele frequencies from simulations matched quite well with experimental data (figure 3A).

Hitchhiking of neutral variants as a consequence of selection on nearby mutations is a likely cause of spatial patterns of nucleotide diversity throughout genomes [7], [8], [9].

The distribution of common nsSNPs was biased towards a lower level of conservation, as would be expected for neutral variants with little or no functional significance.

When neutral variants comprise a large proportion of the total variants, the selective grouping is still low-powered, and more specialized approaches are expected to emerge.