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In classical conditioning, preceding an unconditional blink-eliciting stimulus with a neutral conditional stimulus at a fixed temporal delay, an interstimulus interval, gives the conditional stimulus the ability to elicit a blink that is timed to that interval.
In fear-conditioned memory, acquisition refers to the process in which an association between a neutral conditional stimulus (CS) and an aversive unconditional stimulus (US) is formed through the pairing of the CS with the US.
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Let (text {MtM}^{i}_{t}) be the mark-to-market of the i-th netting set, i.e. the trade additive risk-neutral conditional expectation of future discounted promised cash flows, ignoring counterparty risk and assuming risk-free funding.
They showed that most of these genes differed across environments, which supports the view that local adaptation involves alleles that are beneficial in one environment but neutral elsewhere (conditional neutrality), rather than alleles that are beneficial in one environment and deleterious in another (antagonistic pleiotropy) (Colautti et al. 2012).
Significance for all statistics was assessed (α < 0.05) using empirical distributions based on 10 000 replicates of the neutral coalescent conditional on the observed S and sample size, as described by Ramos-Onsins and Rozas (2002).
We performed χ tests to compare the number of observed events at frequencies 1, 2, and ≥3 with the number expected under the infinite-sites model where the ancestral state in unknown, the number expected under the neutral model conditional on our ascertainment scheme and the number expected under the demographic model inferred by Li and Stephan (2006).
If one wishes to calculate the fraction of deleterious, beneficial or neutral mutations conditional on at least one mutation having taken place, it suffices to divide the values of p, q, and n above by the expected number of sequences with one or more mutations, 1 - P 0).
Significance was assessed using 100,000 coalescent simulations under a standard-neutral model, simulated conditional on the observed number of segregating sites and pattern of sequencing coverage in each region.
Alternatively, under conditional neutrality some alleles may be favoured in one environment but neutral at other locations.
Furthermore, it is possible that local adaptation involves only weak antagonistic pleiotropy or conditional neutrality, where a beneficial allele in one environment has only small deleterious or neutral effect in other environments.
The same holds for ordinary neutral semantics that make conditionals true whenever their consequents are true.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com