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A significant progression in symptom occurrence is noted for all categories of neuropathic problems by glycemic status.
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Neuropathic foot problems by glycemic status are listed in Table 3. Overall, 34 participants (7%) had neuropathy.
When evaluating the efficacy of therapeutic footwear in patients with neuropathic foot problems, patient feedback is inadequate because of the presence of neuropathy.
Therefore there is a significant lack of large, population-based data defining the size of the neuropathic pain problem and attempting to provide some explanations toward pain etiology.
OC patients have to deal with a range of treatment-related symptoms such as hematological side-effects, gastrointestinal problems, neuropathic pain, menstrual changes together with climacteric symptoms, and fertility issues [ 8- 10].
The earliest presenting symptoms are typically neuropathic pain and gastrointestinal problems, which can have a substantial impact on health-related quality of life.
4 These estimates include complications in the early surgical phase, such as wound infections and displaced instrumentation; emergency readmissions; and long-term complications, including pressure ulcers, bladder and bowel dysfunction, neuropathic pain, and respiratory problems.
With an estimated 33 million people living with HIV and more gaining access to ARV every day, the management of HIV-SN associated neuropathic pain is a problem of major global significance.
Neuropathic pain is a problem associated with and prevalent in many musculoskeletal conditions such as low back pain [ 14], acute or chronic radiculopathy [ 12] and syndromes such as cervico-brachial pain syndrome [ 10, 15].
However, because antidepressant medication is prescribed for other problems, such as neuropathic pain [ 36, 37] or sedation, this also may have artificially increased the incidence rate, particularly among people with diabetes.
Neuropathic pain is a large clinical problem, not least such pain affecting lower extremities.
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