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Oxygen and glucose deprivation (OGD) was previously shown to decrease neuronal NADH levels but not astrocytic ones, and neurons were seen to be more susceptible to OGD-mediated cell death [ 26].
At 2 days post-CFA injection, some homogenously stained neurons were seen in addition to the positive SGCs (Additional file 1: Figure S1b, arrow head).
Numerous stained neurons were seen in transgenic control mice, indicating Aβ accumulation in these neurons.
As expected, many EGFP-immunostained (EGFP-ir) neurons were seen in the SCN (Figure 1G, see below for details).
In the caudal medulla, AP+ neurons were seen in the dorsal motor nucleus of the tenth (vagus) nerve (Figure 4K,L).
These neurons were seen as bright fluorescent spots of various sizes (∼10 20 µm) against the background of the darker undifferentiated and unlabeled tissue.
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In both cases, no doubly labeled neurons are seen in the DRN.
Notably, the medial preoptic area was the single area where greater activation of neurons was seen with a preference for pup-associated versus cocaine-associated cues.
The regenerative capacity of these neurons is seen also after lesion in the ventral funiculus of the spinal cord, i.e. within the CNS compartment.
As shown in the right panel of Fig. 2b, the hyperpolarizing shift in RMP of control cells during development, and the lack of this developmental change in AS neurons, was seen uniformly across all cell morphologies and locations.
Recently, activation of CREB within mouse cultured trigeminal ganglion neurons was seen after treatment with CGRP via Ca2+-dependent mechanisms [9].
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CEO of Professional Science Editing for Scientists @ prosciediting.com