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Habituation, as a basic form of learning, is characterized by decreasing amplitudes of neuronal reaction following repeated stimuli.
This nuclear hypertrophy may represent an early neuronal reaction to Abeta or Tau, or a compensatory mechanism which forestalls the progression of AD and allows the brain to resist the development of dementia.
Fast and precise neuronal reaction requires that SVs are clustered in front of the release site, the presynaptic active zone.
With time these lesions evolve into chronic lesions that exhibit a glial and microglial reaction as well as a neuronal reaction which includes thinning of dendrites in the adjacent tissue.
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The training leads to sharp individual neuronal reactions, neurons become specific to one pattern.
At the beginning, neuronal reactions are chaotic.
For that reason, physiological adaptations that are observed at the hypometabolic state in hibernation are potentially analogous to neuronal reactions to a hypometabolism in very early stages of AD.
The neuronal reactions for HNE and MDA in idiopathic autism were stronger than in control brains.
In dup(15)/autism the neuronal reactions for MDA were stronger than in control brains and in idiopathic autism.
"In order to support research on the role of cell biological principles (genomics, proteomics, signaling cascades and reaction dynamics) on the dynamics of neuronal response in health and disease, NEURON's Reaction-Diffusion (rxd) module in Python provides specification and simulation for these dynamics, coupled with the electrophysiological dynamics of the cell membrane.
The upregulation of NOS in our study most likely represents a neuronal plasticity reaction to SAP.
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