In neurons, Ca2+ signaling maintains synaptic transmission, neuronal development and plasticity (Blazejczyk et al. 2009).
Neuronal development on nanostructured and non-nanostructured microprobes was characterized using PC12 neuron-like cells.
Asparagine is an essential component of those proteins that are concerned with signalling, neuronal development and transmission across nerve endings.
The findings, reported in the journal Stem Cell Reports, indicated that defective GRN altered the Wnt signalling pathway, which plays an important role in neuronal development.
Zinc finger transcription factor, Zic2, is an important factor in neuronal development.
We assessed the neuronal development of PC12 cells on uncoated, nanostructured microprobes.
In addition, axonal lengths were measured to evaluate the progress of neuronal development.
It has been demonstrated that AFP plays a role in neuronal development because it serves as the binding protein for arachidonic acid (AA) and docosahexaenoic acid (DHA), which are important for neuronal development (Mizejewski, 2004).
However, the role of miR-29 family during neuronal development remains obscure, which still needs further investigation.
These mice show defects in neuronal development and myelination (Brites, 2003; Rodemer et al., 2003; Teigler et al., 2009).
TET proteins play important roles in neuronal development; however, the regulatory mechanisms of TET family proteins remain largely unknown.
