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The answer lies in the multitude of tiny modifiable connections between neuronal cells, the information-processing units of the brain.
Apoptosis also shapes brain development, in that a vast number of neuronal cells present in the early stages is gradually eliminated.
But it has also been shown that it is important in disease development, such as in Parkinson's disease, which is characterised by the accumulation of protein aggregates in neuronal cells.
However, the effect of GH on neuronal cells remains unknown.
The peptide also entered glial and neuronal cells.
A method to favour the differentiation of the neuronal cells was also developed since the final aim of this work is to develop a biosensor for odour detection using differentiated neuronal cells as transducers.
Both TiO2-S and TiO2-D induced no oxidative stress in human SH-SY5Y neuronal cells.
However, attachment of neuronal cells to the microelectrode surface was not enhanced.
In addition, other metallic nanomaterials were able to induce apoptosis in neuronal cells.
Neuronal cells in the brain are highly sensitive to oxygen for energy production and neuronal activity.
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Overexpression of SOD1 in neuronal cells protects against the toxic effects of Aβ in cultured neuronal cells [45], [46].
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