In addition to cardiac markers, markers of neuronal, bone and cartilage development are included.
Notch signaling is a highly conserved pathway, implicated in cell-fate decisions and differentiation of epithelial, neuronal, bone, blood, muscle and EC.
Here, cell fate could be directed by substrate stiffness in direction of neuronal, bone or muscle progenitors (Discher et al., 2009; Engler et al., 2006).
Such a specific behaviour could have wide-range applications in the biomedical field, not only concerning those cellular systems (neuronal and bone cells) sensitive to electrical stimuli, but also other cell systems.
Dezawa, M. et al. Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation.
Herein, the extremely low frequency electromagnetic fields (ELF-EMF; 50 Hz, 1 mT) exposure synergistically increased biological efficacy of neuronal differentiation in bone marrow-derived human mesenchymal stem cells (hMSCs) grown on graphene-coated substrate.
Sensory and sympathetic nerves and their neurotransmitters are important neuronal effectors regulating bone and cartilage physiology and playing decisive roles in musculoskeletal pathophysiology.
Shortly after, Mezey et al. [ 126] and Brazelton et al. [ 125] simultaneously described spontaneous acquisition of cells bearing neuronal antigens, from bone marrow cells infused intraperitoneally in rats which had migrated to the brain of host animals.
Benestad, H. B., Strøm-Gundersen, I., Iversen, P. O., Haug, E. & Njâ, A. No neuronal regulation of murine bone marrow function.
In results, chemotherapy correlates with severe cardiac, neuronal, hepatic, kidney, and bone narrow toxicity [35, 36].
Therefore, we studied the neuronal differentiation efficiency of bone marrow mesenchymal stem cells (MSCs) from APP695 transgenic mice, which share features of human AD.
