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The neuron with the highest response can be found based on the available colour scale.
Fig. 12 Surface plot of Tanimoto similarity coefficients for the neuron with the highest response value.
The same neuron as before (i.e. the neuron with the highest response at the position [1, 7]) was selected to calculate Tanimoto similarity coefficients to all other neurons.
Since the MLP generates one estimate per time step, we obtain an utterance-based estimate by simple temporal averaging and subsequent selection of the output neuron with the highest average activation (winner-takes-all approach).
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Overall, neurons with the highest Δthreshold values had the most multiplicative responses.
In the present study, we demonstrated for the first time that SKF83959 and other substituted phenylbenzazepines inhibited the delayed rectifier K+ current (IK) in rat hippocampal neurons with the highest inhibition produced by SKF83959.
They also demonstrated a widespread projection pattern for these neurons with the highest density of terminals observed in the paraventricular nucleus (PVN) and the dorsomedial hypothalamus (DMH) [ 14,15,18].
These data show that the timing of let-7 induction in Drosophila MBs and the temporal establishment of α/β lobe neuron identity correlate with the highest ecdysone peak, and perturbation in ecdysone signalling or let-7 deficiency causes morphological defects in the α/β lobes.
Concurrently, H2O2-treated neurons also treated with the highest dose of Nano-CON showed cell viability comparable to that of H2O2-alone.
Proteomics analysis confirmed the presence of several proteins associated with inflammation across all sample groups, but HSEs with neurons had the highest amount of detected protein due to the complexity of the model.
With this aim and considering that the neuron is the cell with the highest number of mitochondria [ 23], we differentiated iPSCs into motor neurons (Fig. 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com