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In this case, the transient memory trace induced by the external stimulus would gradually wane as the neuron trajectory converges to the stochastic attractor corresponding to a given noise realization.
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The second variant, SOGR-IB [ 38, 39], addresses two problems with the original SOGR algorithm: The SOGR algorithm updates the weights after each new instance is presented to the network; as a result, the neuron trajectories can oscillate wildly.
In this case, the memory about the previously received inputs, intended as the input-specific perturbation of the neuron's trajectory, persists for an infinite amount of time.
Plots are histograms normalized by total numbers of samples, each computed for one neuron on one trajectory.
Plots are histograms normalized by total numbers of samples (numbers shown), each computed for one neuron on one trajectory.
(B ) Lap-by-lap spike raster of a WT and a Tau neuron on one trajectory of the track (see Figure 2 for details).
(A ) Lap-by-lap spike raster of six WT neurons and that of five Tau neurons on a trajectory (arrow : running direction).
The median lap SI of WT neurons was only slightly (21%) greater than that of Tau neurons, but the median trajectory SI of WT neurons was much greater (180%) than that of Tau neurons.
Second, we examined whether Tau neuron sequences were trajectory-selective. On both the familiar and novel tracks, most animals ran two different trajectories (back and forth between two food wells) in each of the two running sessions.
We assigned letter identifications to active neurons on a trajectory.
In addition, in the non-sclerotic hippocampus, direct comparison between AT8 and dynorphin sections highlighted that neurons in the trajectory of a normal mossy fibre pathway [a component of the indirect hippocampal pathway with major input from the entorhinal cortex (Duvernoy and Cattin, 2005)], were relatively delayed in tau accumulation compared with adjacent subfields.
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