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A significant effect of GABAergic cell location along the anterior posterior and medio-lateral axes on neuron sensitivity to hypoxia was detected.
Motor neuron sensitivity correlates with the NO-dependent formation of 3NY, which is significantly more pronounced in motor neurons when compared with oligodendrocytes, suggesting peroxynitrite as the toxic molecule.
Thus, the up-regulation of itch and inflammatory receptors in sensory neurons strongly indicates a role for TRPA1 in chronic pruritus and CNI via the enhancement of sensory neuron sensitivity to itch and inflammatory mediators.
The expression profile of the DA transporter and DA autoreceptors, as well as the extent of VTA DA neuron sensitivity to neurotransmitters all depend on which target the VTA DA cell innervates [73] [74] [75].
NRT thresholds, adjusted for scalar placement and impedance, may reflect auditory neuron sensitivity across the cochlea.
DA neuron sensitivity to 6-OHDA was assessed as described previously (Nass et al. 2002, 2005; McDonald et al. 2007).
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General properties of single neuron sensitivities are outlined whereas their relationship to the anatomical circuitry and the underlying functional transformation is described.
Here, we show that AP magnetic sensing can be realized with both single-neuron sensitivity and intact organism applicability using optically probed nitrogen-vacancy (NV) quantum defects in diamond, operated under ambient conditions and with the NV diamond sensor in close proximity (∼10 µm) to the biological sample.
Across the population of visual neurons, sensitivity began declining ∼80 ms before saccade onset.
We found that inhibition of GSK3 almost completely blocked migrating neurons' sensitivity to Sema3A gradient steepness (Fig. 6a, b), even though the cells still showed more migration than Blank-control group without any chemotactic factors.
Using this platform, we systematically studied neurons' sensitivity to the steepness of three classical guidance molecules, including netrin-1, nerve growth factor (NGF), and Sema3A, and revealed dramatic diversity and complexity in relevant chemotactic regulations.
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