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(B ) Quantification of the time to maximum ΔF/F following stimulus change for individual wild-type young (black dots) or aged (blue dots) neuron responses to medium BZ, in seconds, for the subset of odor responsive recordings only.

We then tested these models by recording in vivo receptor neuron responses to a new set of odorants and successfully predicted the responses of five out of seven receptor neurons.

The relationship of different neuron dynamics to phase plane structures that approximate the firing threshold has been developed as a diagnostic tool to understand variable neuron responses to fluctuating environmental parameters (see, e.g., [30] and references therein).

E2 and G1 (10 nM) significantly potentiated pyramidal neuron responses to excitatory inputs when applied to hippocampal slices.

We next compared the GLM to the more traditional STRF estimation method, NRC, in the ability to predict single neuron responses to zebra finch songs and ml noise.

We found that NS neuron responses to electrical stimulation never occurred at latencies shorter than 7 ms after strychnine (n = 4, not shown).

The neuron response to these i.p. injections was determined by the differences between the maximum of fluctuation on a 3 min period before and after injection.

Asperparaline A (100 nM) reduced the maximum neuron response to ACh with a minimal shift in EC50, suggesting that the alkaloid is non-competitive with ACh.

Representative Movie Illustrating the Ilp7 Neuron Response to Yeast, Only GCaMP Channel Is Shown, Related to Figure 5 Movie S2.

Representative Movie Illustrating the Ilp7 Neuron Response to Reduced O2 Availability, Only GCaMP Channel Is Shown, Related to Figure 5 Document S1.

Furthermore the adaptation of the neuron response to stimulation has been shown to be mainly determined by the vesicle release machinery [ 10].