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neuron death?
Mechanisms of Neuron Death. 3 Units.
Cell and molecular biology of neuron death during neurological disease.
Amyotrophic lateral sclerosis (ALS) is caused by motor neuron death.
Uchiyama, Y., Koike, M., Shibata, M. & Sasaki, M. Autophagic neuron death.
Studies in mice show that failed or sluggish autophagy causes neuron death.
Frakes, A. E. et al. Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis.
Sapolsky, R. M. Stress, The Aging Brain, and The Mechanisms of Neuron Death (MIT Press, Cambridge, Massachusetts, 1992).
Cleveland, D. W. & Rothstein, J. D. From Charcot to Lou Gehrig: Deciphering Selective Motor Neuron Death in ALS.
Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease involving motor neuron death, paralysis and, ultimately, respiratory failure.
These findings may lead to a way to prevent motor neuron death in patients and potentially prolong life.
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