Sentence examples for neuron damage in from inspiring English sources
Therefore, the present study was designed to investigate the temporal component of the hippocampal pyramidal neuron damage in the rat brain subjected to chronic HH exposure.
We analysed whether astrocytes express ephrin-B1 ligand, a binding partner for EphB1, following facial axotomy-induced motor neuron damage in the FMN, providing a theoretical basis for EphB1 evoked neuron-to-astrocyte signalling.
During the early stage of cerebral ischemia, it was thought that the BBB disruption and glial cells damage played a more important role than neuron damage in the pathogenesis of cerebral ischemia.
Previous studies demonstrated that pinocembrin can be used as neuroprotective against cerebral ischemic injury with a wide therapeutic time window, which may be attributed to its antiexcitotoxic effects [ 89] and decreased glutamate-induced SH-SY5Y cell injury and primary cultured cortical neuron damage in oxygen-glucose deprivation/reoxygenation (OGD/R).
Although IL-1β expression in the retina has been previously documented (Grigsby et al., 2014; Scuderi et al., 2015), our data show a clear correlation between microglial activation, IL-1β production, and neuron damage in the diabetic retina of CX3CR1-KO mice.
We have previously reported lymphocytic infiltration and neuron damage in myenteric ganglia when full-thickness biopsies from the jejunum in 10 patients with severe IBS were investigated [ 5], and there are many reports that have highlighted signs of an activated immune system as a putative pathogenetic mechanism in IBS (for review see de Giorgio [ 6]).
Further evidence suggested that DMC preserved the functional integrity of baroreceptor neurons by preventing neuronal damage in the nucleus ambiguous and by restoring the expression of AMPA receptors containing GluR2.
Taken together, these data suggest that deficiency in Nurr1 expression may enhance susceptibility to neuronal damage in DAergic neurons, which leads to PD- like symptoms in animals or man.
The finding contributes to a newly emerging picture of how neuron damage occurs in Alzheimer's disease.
The role of DBP in ALS is not known, but it is tempting to speculate that motor neuron damage resulting in the systemic release of actin and ensuing intravascular coagulation and local hypoxia-induced oxidative damage may be mitigated by the actin-scavenging properties of DBP.
Continued understanding of this glutamate BDNF cross-talk may provide an approach with which to enhance the viability of both OLG and proximate neurons damaged in a host of degenerative diseases of the CNS.
