Sentence examples for neuron as a consequence from inspiring English sources

Such non-cell-autonomous toxicity of Aβ has long been suspected (Busche et al., 2008); however, to our knowledge, this is the first in vivo demonstration of toxicity in one neuron as a consequence of Aβ being expressed explicitly by its neighbours.

Our focus is on demonstrating a decrease in the firing rate of excitatory neurons as a consequence of the known effects of anesthetic agents on single neurons.

These data imply that developing neurons are more vulnerable to degenerate than mature neurons as a consequence of forebrain WT and mutant α-syn overexpression.

Mechanistically, this has been partially attributed to neurodevelopmental disruption of the dopamine neurons, as a consequence of exacerbated maternal immunity.

The expression of Tyrosine hydroxylase (Th) can also be used to assess the condition of Purkinje neurons in the cerebellum in NPC disease since Th is ectopically expressed in cerebellar Purkinje neurons as a consequence of the disease (49).

Relative increase of nitrergic, enteric neurons as a consequence of selective loss of cholinergic neurons has also been observed with ageing in both animal experiments and human studies (Santer 1994; Phillips et al. 2003; Bernard et al. 2009).

The inability of the brain to deal with chronic proteotoxic stress in neurodegenerative conditions, such as in Alzheimer's disease, Parkinson's disease and Huntington's disease, led to speculations that the HSR is compromised in neurons as a consequence of ageing.

Capsaicin's use in the treatment of chronic pain is due to an analgesic effect that is explained by capsaicin's action of depletion of stores of substance P from primary sensory neurons as a consequence of the reduced production of prostaglandin [ 39, 60].

While it is notable that both decreased WNT7A and increased proNTF3 could result in loss of synaptic trophic support in response to stress, this is only one of many possible pathways that could be negatively impacted in layer 2/3 neurons as a consequence of Wfs1 deletion.

To exclude de novo expression of TG6 in neurons as a consequence of culture conditions, freshly isolated cells from the cerebral cortex of newborn mice were double-labelled with antibodies to TG6 and to the above cell lineage markers and analysed by FACS.

Numerous studies showed that many neurons die as a consequence of apoptosis.