The frequently-changing terminology for such ailments includes "functional", "psychogenic", "non-organic", "somatoform", "idiopathic", and "medically-unexplained", along with the largely-historical terms "hysteria", "hysterical neurosis", and "hysterical conversion," and the now-exclusively-neurological "conversion disorder".
DSM-5 emphasizes this approach in the accompanying text and mentions singular specific positive neurological signs of conversion (e.g. Hoover's sign) - but abstains to use these directly in order to fulfill criterion (B), i.e. to operationalize more specifically.
In this case report we will emphasize the impact of a comprehensive and ongoing psychosomatic and neurological diagnostic assessment of conversion disorder.
The Diagnostic and Statistical Manual of Mental Disorders, DSM-5, made an attempt to improve diagnostic criteria of conversion disorder (functional neurological symptom disorder).
The concept of using iPSCs and lineage conversion to study neurological disease appears straightforward: Both of these approaches allow for the generation of patient-specific neurons, which are relevant to the disease of interest, and when these are compared to neurons generated from healthy controls, any differences identified could be related to the disease.
Conversion disorder or functional neurological symptom disorder (terms which we will use interchangeably) is common in clinical practice, making up one third of neurology outpatients and approximately 9% of inpatients [ 1, 2].
Dysfunctional emotion processing has been discussed as a contributing factor to functional neurological symptoms (FNS) in the context of conversion disorder, and refers to blunted recognition and the expression of one's own feelings.
Our own research group is using hypnosis to simulate changes in control of the body, in part to examine whether similar brain processes are involved both in hypnosis and a condition called conversion disorder – where what seem to be neurological symptoms appear, like paralysis or blindness, despite there being no damage to the nervous system that could explain them.
"Conversion disorder really refers to people who've developed symptoms like paralysis, or movement disorder, so some kind of neurological symptom," Dr. Jon Stone, a professor of neurology and expert on functional disorders, told VICE.
According to recent research, diagnosing MCI at its early stage and taking corresponding measures to protect certain neurological functions of patients will help to slow down the conversion from MCI to AD.
Neurologic progression was defined as the observation of positive cytology results after confirmation of a negative conversion, or evidence of leptomeningeal disease progression upon neurological examination [ 10, 11].
