Sentence examples for neural vulnerabilities from inspiring English sources

While OBP are at elevated risk for BD, modifiable risk factors that may exacerbate neural vulnerabilities in OBP remain under-characterized.

Our aim was to establish a baseline expression of the chaperone network to provide a framework to explore the basis for neural vulnerability.

With regard to neural vulnerability to sleep deprivation, the PFC shows complicated hemodynamic or metabolic patterns during cognitive performance after sleep deprivation [31] [33].

Although hemodynamic or metabolic responses to sleep deprivation on various cognitive tasks may be influenced by the task difficulty and weight of contribution from PFC activity [37], the neural vulnerability of the PFC to sleep deprivation must have consistent repercussions on cognitive performance.

The significant interaction between depression and IL-17 concentrations predicting MMSE scores suggests that depression may confer neural vulnerability to IL-17 mediated inflammatory pathways.

Impairment in neurogenesis may compromise the extent of plasticity of the hippocampus and their associated neural circuits leading to enhanced neuronal vulnerability and functional detriment.

Although neural selective vulnerability is not uncommon in mitochondrial-associated diseases, including Leigh syndrome, Leber's hereditary optic neuropathy and Alpers' syndrome (Bianchi et al., 2011; Koopman et al., 2013), further studies will be required to understand the mechanisms underlying the progressive tissue-specific nature of mitochondrial disease.

Together with the above findings, these may suggest different neural mechanisms for vulnerability to hypomanic or manic episodes in individuals with bipolar I and II disorder that is, heightened sensitivity to reward anticipation in bipolar II disorder but to reward receipt in bipolar I disorder.

In this review, we summarize advances from affective neuroscience using neural measures to assess vulnerabilities in youth at high risk for depression due to parental history of depression or temperament style, as well as prospective designs evaluating the predictive validity of these vulnerabilities for symptoms and diagnoses of depression across development.

However, future studies should further clarify the relevance of neural network characteristics regarding vulnerability to neurodegenerative effects.

Although NPC is a rare disease, genetic analysis of the associated neuropathology promises to provide insight into the logic of disease neural circuitry, selective neuron vulnerability and neural-glial interactions.