Exact(3)
Besides maintaining ESCs in an undifferentiated, pluripotent state, Sox2 promotes neural over epidermal fate in ectoderm (Zhao et al., 2004; Takemoto et al., 2011).
42 In addition, these patients also show increased plasma noradrenaline and decreased plasma adrenaline levels (very high noradrenaline:adrenaline plasma ratio), which is consistent with the predominance of neural over adrenal sympathetic peripheral branch.
It is surprising that a gene that leads to reduced Wnt and FGF signaling in primitive streak epiblast does not affect cell adhesion and E-cadherin expression (data for which is not shown) nor the balance of Sox2/T expression in this cell population which would lead to cells adopting a neural over a mesodermal fate.
Similar(57)
Pan-neural over-expression of activated Rac or Cdc42 in a fra mutant also induced a significant loss in commissures, but axons did not exit the CNS.
In contrast, pan-neural over-expression of Robo1 did not generate ectopic crossing.
Pan-neural over-expression of Robo2 produces a phenotype in which some axons are repelled from the midline, and some axons ectopically cross the midline, reflecting Robo2's two opposing activities in regulating midline crossing.
Meet the Puppy Slug, the internet's newest cyborganic species: the dog of Google's Deep Dream, or the result of a thing called an artificial neural network over-interpreting an image.
Early in development, Geminin acts as a neural inducer: over-expression of the protein causes expansion of the neural plate at the expense of the epidermis [5].
Apparently, the remaining neural groups take over the job of the lost cells.
Wood explains that as our habits take over, neural activity shifts from working memory to cue-response association -- basically shifting from the intentional mind to the habitual mind.
Indeed, studies combining TMS with functional brain imaging have shown that TMS over one cortical area can induce changes in neural activity over the whole brain [77 80].
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