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Among the remaining 515 TF networks searched, a number of qualified classifiers were found for each of 15 chemical-tissue conditions (Table 3) from a total of 255 unique networks, with one per TF network per condition.
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Rodriguez and colleagues have looked more deeply into the nature of the networks, searching for what they call "flow motifs": extended sequences of consecutive passes between specific players.
The network searching itself isn't easily parallelisable.
In terms of intercommunication through the network, searching for the optimal location is independent to searching for the most optimal route and throughput computation.
According to Careerbuilder, forty-five percent of companies did social network searches when making hiring decisions in 2009.
AMC recently renewed "Hell On Wheels" for a third season, but then announced its pickup was on hold after showrunner John Shiban left the series while the network searches for a replacement.
However, in both cases, a heuristic approach was used to extend small connected components of the PI network, searching for patterns in a combined network which superimposed both physical and genetic interactions.
Therefore, we can say that the network searching algorithm we proposed overcame the limitation when detecting dense sub-networks.
In order to address this problem, we developed a Bayesian network searching algorithm that incorporates prior biological knowledge.
The most common approach to identify key nodes consists of obtaining networks from high throughput data and having obtained the network, searching for the most connected nodes (hubs).
At the same time, tests using only clustering coefficient shows comparable prediction accuracy, which means that the proposed network searching algorithm is effective for detecting protein complexes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com