Two-way repeated measures ANOVAs were performed separately for each sub-network, with factors of ROI (Core: 4, MTL: 9, DMPFC: 7) and switch type (no-switch, dissimilar-task-switch). Main effects of task-switching were found for the Core (F 1,17) = 16.7, p = 0.001) and MTL (F 1,17) = 6.1, p = 0.03) sub-networks, showing increased activity for dissimilar switches.
This is in line with recent paradigm where microRNAs regulate self-renewal and differentiation pathways of embryonic stem cells by forming an integral biological network with transcription factors.
In view of these findings, we here investigated if Npm1 and Tpt1 network with other factors identified as important in iPS cell creation and ES cell maintenance.
This is in line with recent paradigm where miRNAs regulate self-renewal and differentiation pathways of embryonic stem cells by forming an integral biological network with transcription factors [ 29].
In [15], Al-Nabhan et al. proposed three similar centralized algorithms to construct CDSs in wireless network with approximation factor of 5.
By further integrating the co-expression network with transcription factor binding analysis, we identified candidate regulators for disease-associated modules, including NFAT [ 19, 20], MEF2 [ 17, 18], CREB [ 21- 24], and forkhead box proteins O (FOXO) [ 29- 32].
In the preferential attachment model, we evaluated the degree distribution of the two biological networks (G Y u and G DIP ) and used the Barabási-Albert algorithm to construct a scale-free network with attachment factor 1.5 (each iteration adds a new vertex with 1 ~ 2 edges attached to existing vertices).
Polyploidy events also influence other kinds of duplication, thereby creating a network of factors with mutual influence.
A similar process has been observed for gene regulatory networks, with transcription factors-the key organizers of the genes transcriptional activity-being preferentially lost during the adaptation to a host-associated lifestyle [ 30].
This produced a network with 118 transcription factors linked to 3942 target genes.
We created an annotated network of these 20 genes entitled the 'Viral infection network', with the transcription factors MYC and P53 serving as the central hubs of this network (Fig. 3).
