Sentence examples for network of residue from inspiring English sources

Signal propagation has been recently argued to occur via multiple allosteric pathways, embedded in the network of residue contacts (5).

The Q155N substitution significantly disrupted the hydrogen-bond network of residue 155 with Ala194, Asn195, and Glu159, decreasing from nine (wild-type) to three (Q155N; Figure 5b).

Our results reveal that a dynamically coupled network of residues extends from the substrate-binding site to a surface loop.

Using the metabolic enzyme dihydrofolate reductase as a model system, we show that: (1) the sector is strongly correlated to a network of residues undergoing millisecond conformational fluctuations associated with enzyme catalysis, and (2) sector-connected surface sites are statistically preferred locations for the emergence of allosteric control in vivo.

The detachment kinetics from actin upon ATP binding is a key step in the reaction cycle of myosin V. We show that a network of residues, constituting the allostery wiring diagram (AWD), that trigger the rigor (R) to post-rigor (PR) transition, span key structural elements from the ATP and actin-binding regions.

To determine the magnitude of the evolutionary plasticity of GroEL and GroES, we first conducted a coevolutionary analysis to determine the network of residues dependencies in all bacteria.

(B ) Zoom in of binding pocket (as dotted lines in (A )) showing flexible β -sheet for C=O·HN network of residues 55-62-113-98 in neighbouring β -strands.

For simpler DNAPs and RNAPs, a network of residues spanning the fingers and palm domains was detected to be involved in the open ↔ closed transition.

Are these determinants just a small group of residues localized in close proximity to the substrate as currently thought, or do they form a sparse network of residues instead?

This helix is part of the dsRNA-binding domain of VP35 that is involved in the formation of the asymmetric VP35 RBD dimeric interface in Reston Ebola virus through a hydrogen-bonding network of residues and a solvent molecule.

The mechanism by which PhoQ is activated by acidic pH appears to be distinct from CAMP and involves perturbations to a network of residues surrounding H157 within the α/β-core of the PD (Prost et al., 2007).