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Analysis of the biological processes in which these proteins are involved showed that virtually all of these plasma proteins are linked to a network of mechanisms that regulate protease activities, natural immunity, lipid turnover, coagulation pathways, and metabolism of the extracellular matrix.
A complex network of mechanisms involving induction of lineage instructive transcription factors, installation or removal of histone modifications and changes in the DNA methylation pattern locally orchestrate the three-dimensional chromatin structure and determine cell fate.
A plausible network of mechanisms in accord with these observations is illustrated in Fig. 4.
DOI: http://dx.doi.org/10.7554/eLife.02024.001 Gene expression is controlled by a complicated network of mechanisms involving a wide range of enzymes and protein complexes.
We therefore sought to investigate the exocyst's role within the integrated network of mechanisms that regulate and produce primary root growth in Arabidopsis thaliana, focusing on the hypothetical auxin- and brassinosteroid-related mechanisms.
These studies reveal that epigenetics is a complex network of mechanisms that work together in creating an "epigenetic landscape" for the regulation of gene expression at transcriptional and translational levels.
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Appetite, satiety, and reward mechanisms regulate food intake by a complex network of internal mechanisms and environmental factors.
This network of competing mechanisms should be reconciled with existing disorganized or driver mechanisms for AF, to improve clinical mapping and ablation of persistent AF.URL: http://www.clinicaltrials.gov.gov
A complex network of molecular mechanisms involved in the recognition and activation processes of bacterial infections and their regulation has developed from these studies.
Specific post-translational modifications of core histones are a central component in the complex network of epigenetic mechanisms by which genes are activated and silenced [1].
Taken together, these findings delineate KLK6 as a new player within the network of regulatory mechanisms that govern survival of immune cells.
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