Sentence examples for network of alterations from inspiring English sources

To construct the sequential network of alterations for each tumor, we monitored the presence or absence of each genetic lesion in each sample.

We used 70 CLL patients to analyze evolution network of 32 alterations (one gene can have more alterations by considering mutation sites).

In addition, a large and complex dataset allows for both the investigation of significant results at the individual gene level and provides the ability to determine elaborate networks of alteration.

Gastric adenocarcinoma has a complex network of molecular alterations along its carcinogenesis pathway.

Colorectal carcinogenesis involves a network of genetic alterations that affect DNA repair genes, oncogenes and tumour suppressor genes.

First, we reconstruct the sequential network of genetic alterations in each patient by analyzing genomic data from different time points.

High-throughout quantitative transcriptomic studies have revealed large numbers of gene expression changes (Dhanasekaran et al, 2001; Ashida et al, 2004), which suggest that a broad and complex network of molecular alterations is involved.

GSMs allow one to examine the effect of network alterations by performing in silico gene knock-out and gain-of-function experiments prior to labour-intensive and expensive wet-lab experiments.

We argue that the latter changes are often overlooked as sources of alterations in network behavior when there are also structural (connectivity) abnormalities present; indeed, they may even give rise to the structural changes observed in these states.

Together, our study provides direct evidence of reduced between-hemisphere WM connectivity with greater depressive episodes, and of alterations of network properties with cognitive dysfunction in geriatric depression.

Using the same perturbation analysis as outlined above for the erythrocyte network we investigated the impact of alterations in the values of the Gibb's free standard energies on the predicted flux distributions.