Sentence examples for network marker from inspiring English sources

Next, based on the carcinogenesis relevance value, we investigated the common core and specific network marker of four cancers for multiple drug targets with the aim of suggesting potential and relevant medical therapy for cancer.

Distribution of COMMD1 did not overlap with the ER marker calnexin, the trans-Golgi network marker 58k or the endosomal marker Rab4.

The endosomal marker syntaxin 13 was also enriched in the synaptic membrane and synaptic vesicle fractions whereas the concentration of the trans-Golgi network marker γ-adaptin and the ER marker KDEL was decreased.

The ER-Golgi intermediate compartment marker, ERGIC-53, and the trans-Golgi network marker γ-adaptin had two peaks of which one correlated with γ-secretase activity and the other one was found in lighter fractions.

At all time points we observed strong vesicular staining throughout the cytoplasm, which localized with the late endosome/lysosome marker LysoTracker, but not with the trans-Golgi network marker IGF-IIR (Figure 2A).

This change may reflect the fragmentation of the Golgi that occurs in HSV1-infected Vero cells [48], [68]; the re-organization of microtubules shown here and reported elsewhere [54], [69]; and the redistribution of the trans-Golgi network marker, TGN46, reported to occur in confluent epithelial cell cultures after 12 hr of continuous exposure to herpes virus [50], [70].

Finally, based on 28 significant proteins of core network markers in the carcinogenesis of four cancers, a systems drug design mechanism is introduced to select multiple drug targets for multiple-target cocktail therapies.

The Flag-tag antibody was diluted at 1∶1500 (mouse, Sigma) and the trans-Golgi network marker-38 (mouse, Acris) as well as the endoplasmic reticulum marker protein disulfide isomerase antibody (mouse, Abcam) were diluted at 1∶300.

To target PPIs in both common core network markers and specific network markers simultaneously may provide new directions for anticancer therapy strategies.

We also found 134 significant proteins as specific network markers of early-stage liver cancer and 32 significant proteins as specific network markers of late-stage liver cancer.

Herein, 14 of the total stage network markers identified were involved in the cell cycle pathway.