Exact(5)
Under steady-state conditions, the length of the microtubule is unchanged, as the net tubulin assembly rate equals the net disassembly rate.
Our data propose that stress fibers are maintained or become thicker under tension, whereas mechanosensitive binding of ADF/cofilins to stress fibers that are not under tensions shifts the balance from steady state (or net assembly) to net disassembly.
Purified Aip1 alone has no effect on actin-filament dynamics, but in combination with cofilin promotes the net disassembly of F-actin into monomers and short oligomers (Okada et al. 1999; Rodal et al. 1999; Okreglak and Drubin 2010).
Decreases in actin nucleation and cross-linking proteins (ARPC3 [ 43] and FLNA [ 44]), increases in actin filament severing proteins (CFL1 and DSTN [ 45]) and in proteins that bind to G-actin to inhibit polymerization (CAP1 [ 46] and TMSB10 [ 47]), allude to a net disassembly of the actin cytoskeleton at 25°C.
An alternative model for RecX-dependent inhibition of recombination was based on its proposed ability to cap the growing 3′-end of the RecA filament, resulting in net disassembly of RecA protomers and eventual dissolution of the filament (Drees et al, 2004a).
Similar(55)
Ponti et al. [7] have identified a net network disassembly peak marking the beginning of the transition from lamellipodium to lamellum, which is reproduced by our model.
Serum DNase1 is essential for disassembly of NETs after an infection and Arturo reported that a considerable number of SLE patients' sera do not degrade NETs efficiently.
A biochemical network describing the assembly of the transcription machinery at promoters can be thought of as a series of reversible fluid-flows that dynamically move forward (transcription machinery assembly) and backward (disassembly or inhibition), with mRNA output being the net flux of these forward and reverse flows.
Achieving net benefits with adaptive reuse partly relies on efficiently planning building disassembly.
A novel deadlock control policy in the frame of Petri nets formalism is presented for a class of generalized Petri nets, namely G-systems, which can usually model assembly and disassembly operations of multiple resource acquisition.
Assembly and disassembly events were defined as continuous phases that produced a net change in aMT length of ≥0.5 µm and a coefficient of variation ≥0.85.
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