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# Downsample a time sequence.
This slow convergence has inspired the development of Multi-Level MLMCe Carlo or methodsthods [33 35], in which one consider a nested sequence of space-time grids and draws different number of samples from each grid.
For CADSS, a mixed model analyzed change from baseline, with treatment/dose, period, time point and treatment/dose by time point interaction as fixed effects, with subjects nested within sequence as a random effect and baseline values as a covariate.
qEEG cordance was analyzed using repeated measures analysis of covariance on absolute values, with treatment/dose, period, time point and treatment/dose by time point and sequence as fixed effects, with subjects nested within sequence as a random effect and baseline values as a covariate.
Tacitly nested number sequence.
Explicitly nested number sequence.
This is consistent with the general lack of reversible disembedding when working with a tacitly nested number sequence.
The PCR products were sequenced with nested sequencing primers, which are named 5R_SEQ primers in Table S2.
The types of number sequences, in order of increasing sophistication, are (1) initial number sequences (INS), (2) tacitly nested number sequences (TNS), (3) explicitly nested number sequences (ENS), and (4) generalized number sequences (GNS).
This reconceptualization of counting-on activity results in a reorganization of initial number sequences into tacitly nested number sequences.
For one of these genes, seven different cDNA sequences were amplified using nested PCR and sequenced.
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