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Potassium is important for normal muscle and nerve responsiveness, heart rhythm, and, in particular, intracellular fluid pressure and balance.
To control for time-dependent changes in CT nerve responsiveness, we stimulated the tongue with the reference stimulus immediately (i.e., 40 s) before stimulating it with each of the sugar solutions.
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Sensory nerve fiber responsiveness was measured using a Neurometer.
This arrangement of receptors is largely responsible for the broad responsiveness of the trigeminal nerve and also provides redundant detection mechanisms for many chemicals.
To evaluate the ability of two novel coiled test stimulation lead designs to reduce or eliminate undesired migration and concomitant loss or attenuation of responsiveness to sacral nerve stimulation (SNS) associated with standard percutaneous nerve evaluation (PNE) leads.
As mentioned above, rats and mice differ in the relative contribution of the CT and GL nerves to sweet taste responsiveness (Frank et al. 1983; Frank 1991; Danilova and Hellekant 2003), and they may differ in salt taste responsiveness as well.
Moreover, nerve injury-induced hyper-responsiveness was blocked by the T-channel blocker ethosuximide [ 130], which also attenuated mechanical allodynia in animal models of vincristine and paclitaxel-induced neuropathic pain [ 131].
Both tests have been shown to have excellent discriminative validity and responsiveness in peripheral nerve injuries [ 22, 36, 23].
Several tests of sensibility are available and studies on their validity, reliability and responsiveness in peripheral nerve injuries have been published [ 16], but little is known about their relative responsiveness in patients undergoing surgery for carpal tunnel syndrome.
Exposure of the nose to the malodorants (unpleasant smells) increases the responsiveness of trigeminal nerves, and this mechanism is mediated by paracrine signalling pathway between olfactory and trigeminal nerves [ 30].
Both IL-1 and PgE2 are known to be involved in skin inflammation and itching by decreasing the mechanical threshold and the thermal responsiveness of the sensory nerve endings, which could facilitate CNI (Binshtok et al., 2008).
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