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The conduits were used to bridge a 10 mm gap in a rat sciatic nerve model.
By using a nerve model system composed of some liquid membrane cells, we directly measured the actual membrane potentials and the local currents of the respective cells.
Crosslinked PCLF2000 nerve conduits were selected for evaluation in a 1 cm gap rat sciatic nerve model.
This chapter describes fabrication of a poly(caprolactone) nerve guide and demonstrates its use in a rat sciatic nerve model.
In past studies using the CCI model and the crushed sciatic nerve model, the mean intensity decreased (Vrinten and Hamers 2003; Bozkurt et al. 2008).
In previous studies using a chronic constriction injury (CCI) model (Vrinten and Hamers 2003) and a crushed sciatic nerve model (Bozkurt et al. 2008), stand decreased.
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Currently, the computational auditory nerve models and sparse coding attract much attention from both neuroscience and speech signal processing communities.
This work therefore supports the use of aligned electrospun PCL microfibres for the development of 3D peripheral nerve models in vitro.
Such animal models have two major advantages: firstly, the rat sciatic or median nerve models are the most widespread animal models for peripheral nerve regeneration.
Animal studies in rat sciatic nerve and rabbit common peroneal nerve models have demonstrated improved axon counts and gait function after end-to-end coaptation with a PTB nerve wrap [ 60, 62, 63].
Nerve agent model compounds [ SPGD3N (soman model), SPGB3N (sarin model), and SPGF3N (cyclosarin model)] were used as freshly prepared solutions in DMSO.
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