Kidneys, heart, liver, nerves, gastrointestinal tract and soft tissues are most commonly involved.
Transmission to the vomiting center then occurs either directly from the afferent vagal nerve via gastrointestinal 5-HT3 receptors or indirectly via the chemoreceptor trigger zone (CTZ).
Fabry disease is a rare metabolic storage disorder that results in progressive effects on multiple organs; clinical manifestations include pain from nerve damage, gastrointestinal symptoms, angiokeratoma, corneal changes, and hearing loss.
Research indicates that acupuncture may adjust the function of vegetative nerves, regulate gastrointestinal tract function, protect gastric mucosa and have an antianxiety function that might reduce the concentration of blood 5-HT.
These entities respectively refer to affected (intrinsic and extrinsic) gastrointestinal nerve pathways, interstitial cells of Cajal, and smooth muscle cells (Table 1).
CB1 receptors have been found peripherally on the nerve terminals of gastrointestinal tract neurons (43), liver (44), skeletal muscle (45), pancreas (46) and in adipose tissue (47).
Bone-marrow-derived (BMD) cells have been shown to fuse with hepatic cells, nerve cells and gastrointestinal cells and the theory has been put forward that such fusions may serve to repair damaged or corrupted cells (Alvarez-Dolado et al. 2003; Rizvi et al. 2006; Vassilopoulos et al. 2003; Wang et al. 2003).
The drug eases abdominal pain and diarrhea by acting on nerves in the gastrointestinal tract.
It acts on nerves in the gastrointestinal tract to relieve pain and diarrhea.
In humans, VMAT2 is present in beta cells [ 17, 18] and in the sympathetic nerves throughout the gastrointestinal tract and pancreas [ 19].
