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The end goal would be to replace brain cells lost to Alzheimer's, repair injured nerve cells causing paralysis and treat cancers, malfunctioning organs and other now-irreparable conditions.
Multiple sclerosis is a disease in which the patient's own immune system attacks nerve cells, causing vision problems, numbness, paralysis and other symptoms.
As these cells die, they release toxic chemicals, particularly glutamate, an amino acid that overexcites the surrounding nerve cells, causing inflammation.
As prions replicate by converting normal forms of the protein into their abnormal shape they accumulate within nerve cells, causing neurodegeneration.
Its central feature, they said, was a relentless loss of the insulation that sheathes nerve cells, causing a short-circuit in the electrical signals passing through the cells.
In 1976, a swine flu vaccine was associated with Guillain-Barré syndrome (pronounced ghee-YAN bah-RAY), in which the body damages its own nerve cells, causing weakness and sometimes paralysis.
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They hypothesized that the altered FGFR3 gene, expressed in the brain and nerve cells, caused a primary "brain-based" hypotonia.
It is well-established that a brief depolarization of most nerve cells causes an influx of Ca2+ ions across the plasma membrane and thus a local rise in [Ca2+] i.
To make sure that the cell damage created when the amygdala was surgically destroyed was not affecting the experiment, the researchers borrowed a gene therapy technique from Robert Sapolsky's lab at Stanford University to genetically introduce potassium channels into the amygdala, which shut down the activity of the nerve cells without causing injury.
The angioma irritated brain cells, causing nerves to misfire and bringing on at least one seizure.
M. leprae infects macrophages and Schwann cells, causing peripheral nerve damage which results in sensory and motor loss that ultimately cause the severe disability that is a hallmark of leprosy [ 2].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com