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Some authors have also proposed additional potential associations of clonorchis with other biliopancreatic neoplasms, for instance, pancreatic mucinous cystadenoma [72], although probably further investigations are needed.
Other morphological features can aid in assessing the source of malignant neoplasms: for example, an expansive and septated metastasis would strongly suggest primary renal cell cancer or thyroid cancer, while intralesional calcifications would suggest a mucinous tumor [3].
Cells isolated from paraffin sections can be stored in suspension so that arrays can be created as and when needed from a range of neoplasms for investigation by the immunoFISH technique (for example, for studying a new genetic abnormality).
Small precancerous neoplasms for many pancreatic cancers are being detected at greatly increased rates by modern medical imaging.
Tumours of the pancreas are aggressive neoplasms for which no effective therapeutic strategy is currently available.
Uterine cervical and endometrial cancers are common malignant solid neoplasms for which there are no useful prognostic markers.
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We had 80% power to detect a hazard ratio of 3.6 for neoplasms, 10.0 for liver cancer, 3.5 for endocrinological causes, and 3.6 for circulatory causes.
Disseminated melanoma is a radiation- and chemotherapy-refractory neoplasm for which no standard therapy currently exists.
This results in fabrication of new vasculature to fulfil the nutrient supply of sprouting neoplasm for rapid expansion.
Endometrial adenocarcinoma has been proposed, due to frequent activation of the PI3K/AKT pathway, as a candidate neoplasm for treatment with mTOR inhibitors.
The following example illustrates the identification process of the new indication, bladder neoplasm for Capecitabine.
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