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Type A-response regulators (RRs) negatively regulate cytokinin signaling [ 76].
Conversely, many factors negatively regulate RAD51 nucleofilament formation to ensure strand exchange regulation.
In contrast, HIFs negatively regulate TCA and OXPHOS regulatory genes.
As srGAP3 can negatively regulate neuronal differentiation of Neuro2a cells, we speculate TET1 may negatively regulate Neuro2a cells differentiation via modulating the expression of srGAP3.
We found that all three TET proteins could negatively regulate neuronal differentiation of Neuro2a cells.
Furthermore, non-catalytic TET1 could negatively regulate neuronal differentiation through upregulating srGAP3.
Our previous studies have demonstrated that srGAP3 can negatively regulate neuronal differentiation of Neuro2a cells.
For example, prevalent in animal, microRNAs negatively regulate gene expression by attenuating translation.
PIM1 was found to negatively regulate Sendai virus (SeV -triggered IFN-β promoter activation.
The PtdInsPs-binding proteins, MAP18 and MDP25, negatively regulate cytoskeletal organization.
However, recent findings indicate that PSGL-1 can also negatively regulate T cell function.
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