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Of these mental health conditions, depressive disorder is the main cause of sickness absence (34%) [ 9], and has a more negative prognosis for RTW than other common mental health conditions [ 10].
Co-expression of EGFR and HER2 in breast cancer cell lines has been shown to induce drug resistance, including resistance to TZ [ 17, 18], and has been correlated with a negative prognosis for breast cancer patients [ 1, 11].
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The most well-recognised risk factors for death in patients with CHD are still of great importance for the negative prognosis of patients after PCI.
Lenalidomide appears to mitigate the negative prognosis of non-GCB phenotype.
However, CD151 overexpression was found to be an independent negative prognosis factor for OS but not for DFS of patients with breast cancer in this study.
In our study, CXCR4 tumour overexpression was associated with a higher risk of LN metastasis, liver recurrence and was found to be an independent negative prognosis factor for OS but not for DFS.
In this study CD163+ cells in primary breast tumor tissue were brought up as a negative prognosis factor for RFS.
Hyperactive PI3K/Akt signaling is commonly seen in MPMs due to frequent loss of PTEN expression [ 16] and is considered to be a negative prognosis marker for MPM [ 37].
Moreover, the growing correlation between P-gp expression and a negative prognosis or poor outcome for chemotherapy has sparked significant interest in the generation of inhibitors.
Neovascularisation has been shown to be necessary for tumour growth [14] and many studies have confirmed the negative prognosis in highly vascularised MM.
My mother wasn't going to allow a negative prognosis into my awareness.
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