Your English writing platform
Discover LudwigExact(24)
Obviously, this is the consequence of a very negative primary campaign struggle.
Notably, several patients with HER2 negative primary disease but HER2 positive CTCs have been reported to show clinical benefit from trastuzumab treatment [25], possibly suggesting some diagnostic utility of HER2 characterization in CTCs for determining eligibility for HER2-targeting agents in patients with HER2 negative primary disease.
Triple negative: estrogen, progesterone and HER2 negative primary tumor.
Three negative primary BCs had an AR positive lymph node metastasis (17.6 %; 3 of 17 AR negative primary BCs with evaluable matching lymph nodes).
In each case, species/isotype-matched pre-immune IgGs served as negative primary antibody controls.
For each epitope analyzed, species/isotype-matched pre-immune IgGs served as negative primary antibody controls.
Similar(35)
Amir et al. reported that an HER2-positive primary tumor and HER2-negative metastatic tumor account for 12.5 % of cases, while an HER2-negative primary tumor and HER2-positive metastatic tumor account for 4.6%% of cases [1].
Furthermore, as reported by other investigators [12] [15] we have detected HER2-positive CTCs in women with metastatic BC and initially HER2-negative primary tumors.
In the GeparQuattro trial, HER2 overexpressing CTCs were observed in 14 of 58 CTC-positive cases (24.1%) including 8 patients with HER2-negative primary tumors and 3 patients after neoadjuvant trastuzumab.
Forty-four patients had a HER2-negative primary tumor.
Among 47 (48%) EGFR-negative primary tumours, 35 cases (74%) expressed phosphorylated Akt and MAPK.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com