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This may be due to the strong random mutation induced by physical and chemical mutagenesis, the negative mutation happened in cellulase.
The A. nidulans FGSC1035 strain carries a dominant negative mutation in the guanidine nucleotide binding domain of heterotrimeric G-protein α-subunit (fadA).
The present study has been designed to delineate the effect of cardiospecific dominant negative mutation of 14-3-3η 14-3-3η 14-3-3η-3) on various liproteinabolism DN14-3-3 DN14-3-3 DN14-3-3pressions and cardiac macrophage phenotype in high fat diet (HFD) fed mice.
In very simple terms, if a negative mutation occurred on one of the two X chromosomes, women had the possibility to cope or partially compensate for it.
By contrast, the dominant negative mutation exclusively disrupts the interaction of PTB with fosB I4.
The analogous dominant negative mutation in mouse TLR6 (Pro691His) was reported and characterized previously [41].
Similar(21)
We appreciate the complexity of interpreting negative mutation-specific tests in family members of a carrier of a mutation in one of the moderately penetrant genes on these panels.
An R-negative mutation apparently decreased the efficiency of successful integration by two orders of magnitude.
The structure and properties of the PG-1 dominant-negative mutation demonstrate a mechanism for manipulating Myb gene structure that can provide useful insight into the mechanisms by which MYB transcription factors function to regulate gene expression in plants.
These observations would support our interpretation that Sci is a dominant-negative mutation.
A recent study highlighted the problem of false-negative mutation tests by molecular techniques.
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