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Hep3B cells were transiently transfected with dominant negative mutant CKI-ε (KD) (K to R).
Furthermore, the shear stress induction of JNK was attenuated by a negative mutant of Cbl.
A polyhydroxyalkanoate (PHA) synthase negative mutant termed Aeromonas hydrophila CQ4 was constructed from its wild type strain A. hydrophila 4AK4.
Using an RNase H negative mutant RT, we showed that a polymer trap still prevented strand transfer.
Furthermore, dominant negative mutant CHD4 abrogated the inhibitory effect of ectopic Nab2 on Egr-1 activity.
Eps15 is involved in endosytosis, and its dominant negative mutant (Eps15-DN) suppresses endocytosis [37], [38].
Similar(26)
This knowledge was translated into the design of a dominant-negative mutant of Taspase1 (dnTaspase1
Dominant-negative mutant of telomerase hTERT was demonstrated to show selective anticancer effects in tumor cells.
PHA-negative mutant R. eutropha PHB-4 (DSM541) was employed as host strain for PHA synthesis (Schlegel et al. 1970).
The M5-negative mutant ΔM5 has been described [23].
Thus, Lyn inactivation by a dominant-negative mutant allowed an up-regulation of Kit expression.
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