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A negative modulation effect was observed in perigenual cingulate cortex, insula, and medial thalamus (P < 0.05).
At the GABAA-α1 receptor the compound gives low level of negative modulation further separating it from the other compounds.
Naito, Y. et al. Germinal center marker GL7 probes activation-dependent repression of N-glycolylneuraminic acid, a sialic acid species involved in the negative modulation of B-cell activation.
Our results reveal an unexpected function of SWCNT in negative modulation of OSCs, and provide significant implications for the potential CSCs-targeted therapeutic applications of SWCNT.
Keap1 constitutively binds to the transcription factor Nrf2 to promote its degradation, resulting in negative modulation of genes involved in cellular protection against oxidative stress.
Collectively, we drew a conclusion that the favorable antifibrotic effects of ligustrazine were attributed to its negative modulation on HSC behaviors by interrupting Nrf2/β-catenin pathway.
Modulation factors were mild functions of temperature in the first stage and strong functions in the second stage of enzyme inactivation, where galactose positive modulation factors increase while lactose negative modulation factors decrease with temperature.
Positive or negative modulation corresponds to different SCM phase.
This suggests a negative modulation of cleavage by residues 100 104 in this context.
Presumably, the increased NO could open K+ channels and contribute to increased negative modulation of the phenylephrine contraction.
In baboons, negative modulation of GABAA receptor produced effects that varied with the social status of the subject [34].
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