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You try not to carry anything negative forward in your life".
Q3 is less clear, with nearly three times more companies issuing negative forward guidance than positive.
The underlying mechanism for up-regulation of SmKO, SmKAO1 and SmKAO2 (positive feedback regulation) and down-regulation of various SmGA2ox genes (negative forward regulation) in tissues treated with exogenous GA3 remain to be elucidated.
For the validation experiments presented in figure 2 B, we used two different primer sets: positive forward primer 5′-CGAACTTTTTGCTTTTGTTTTTG-3′ and positive reverse primer 5′-CCTGCTAGCCTCCTCCTACC-3′; and negative forward primer 5′-TCCAGCATCACTCAGAAACG-3′ and negative reverse primer 5′-AAAGCCCCTGATAGCCCTTA-3′.
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Thus, iron supplementation may result in aggregation of iron-sulfur proteins that can profoundly affect mitochondrial function, potentially causing a negative forward-feeding cycle, resulting in further iron accumulation.
For reverse side fault the angle is positive and negative for forward fault.
The value of ϕ 1 is positive for reverse fault and negative for forward side fault.
However, its negative innovation forward linkages imply that an improvement in transportation services exerts substitution effects on other sectors, at least in the short run.
Primers amplifying the promoter region of the rat Gapdh gene were used as a negative control (forward, 5'-AAACAAGTTCACCACCATGTGAAA-3'; reverse, 5'-CCAGGGATTGACCAAAGGTGAGTT-3').
ZEB1 is known to be regulated by a double negative feed forward loop involving the miRNA 200 family 30, 41.
Proteostasis regulators such as cystamine interrupt this negative feed forward loop (in which a functional CFTR defect entails the destruction of PM-sessile CFTR protein) and create a permissive environment for the restoration of CFTR function.
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