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BRCA1-associated tumours are more likely to be oestrogen, progesterone receptor and Her2 receptor negative, express TP53 protein, and demonstrate medullary/atypical medullary morphology.
Additional studies have suggested that the expression of ERβ in breast tumors increases the effectiveness of tamoxifen therapy [ 44- 46] and one report found that 47% of breast tumors classified as ERα negative express ERβ [ 33].
Approximately 70% of 'triple-negative' breast cancers (ER negative, PR negative, Her2 negative) express basal markers [ 7- 9], resulting in the triple-negative subtype commonly being used as a surrogate marker for the basal-like subtype.
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p16 expression was examined by light microscopy and scored in tumours as absent (negative), expressed or highly expressed.
After the conference call, Standard & Poor's said it had changed A.I.G.'s credit watch status to negative, expressing concern about whether A.I.G. would be able to restructure with the help of the Fed, as planned.
Much of the press comment was negative, expressing consternation that the heroine was an amoral seductress rather than a woman of virtue.
More CD8+ T cells (both tetramer positive and negative) expressed the early activation marker CD69 after i.n.n
LeX antigen negative expressed H. pylori escape binding to dendritic cells and induce a strong Th1 response.
22 is ER negative, expresses the basal marker CK17, and is PLD1 positive.
Finally, the positive and negative expressed emotions of the interviewed parents are rated by the interviewer.
All those women who were screened negative expressed their intent to repeat the test every three years.
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CEO of Professional Science Editing for Scientists @ prosciediting.com